Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation

BACKGROUND: Cancer metastases are the main cause of lethality. The five-year survival rate for patients diagnosed with advanced stage oral cancer is 30%. Hence, the identification of novel therapeutic targets is an urgent need. However, tumors are comprised of a heterogeneous collection of cells wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Weiße, Jonas, Rosemann, Julia, Müller, Lisa, Kappler, Matthias, Eckert, Alexander W., Glaß, Markus, Misiak, Danny, Hüttelmaier, Stefan, Ballhausen, Wolfgang G., Hatzfeld, Mechthild, Haemmerle, Monika, Gutschner, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194179/
https://www.ncbi.nlm.nih.gov/pubmed/34116687
http://dx.doi.org/10.1186/s12943-021-01384-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194179/
https://www.ncbi.nlm.nih.gov/pubmed/34116687
http://dx.doi.org/10.1186/s12943-021-01384-w

Ejemplares similares