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Metabolic radiolabeling and in vivo PET imaging of cytotoxic T lymphocytes to guide combination adoptive cell transfer cancer therapy

BACKGROUND: Adoptive T cell transfer-based immunotherapy yields unsatisfactory results in the treatment of solid tumors, partially owing to limited tumor infiltration and the immunosuppressive microenvironment in solid tumors. Therefore, strategies for the noninvasive tracking of adoptive T cells ar...

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Detalles Bibliográficos
Autores principales: Lu, Dehua, Wang, Yanpu, Zhang, Ting, Wang, Feng, Li, Kui, Zhou, Shixin, Zhu, Hua, Yang, Zhi, Liu, Zhaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194184/
https://www.ncbi.nlm.nih.gov/pubmed/34112200
http://dx.doi.org/10.1186/s12951-021-00924-2