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Metabolic radiolabeling and in vivo PET imaging of cytotoxic T lymphocytes to guide combination adoptive cell transfer cancer therapy
BACKGROUND: Adoptive T cell transfer-based immunotherapy yields unsatisfactory results in the treatment of solid tumors, partially owing to limited tumor infiltration and the immunosuppressive microenvironment in solid tumors. Therefore, strategies for the noninvasive tracking of adoptive T cells ar...
Autores principales: | Lu, Dehua, Wang, Yanpu, Zhang, Ting, Wang, Feng, Li, Kui, Zhou, Shixin, Zhu, Hua, Yang, Zhi, Liu, Zhaofei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194184/ https://www.ncbi.nlm.nih.gov/pubmed/34112200 http://dx.doi.org/10.1186/s12951-021-00924-2 |
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