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Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice
Complement factor H (FH) is the main plasma regulator of the alternative pathway of complement. Genetic and acquired abnormalities in FH cause uncontrolled complement activation amplifying, with the consequent accumulation of complement components on the renal glomeruli. This leads to conditions suc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194190/ https://www.ncbi.nlm.nih.gov/pubmed/34112227 http://dx.doi.org/10.1186/s13287-021-02386-7 |