Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice

Complement factor H (FH) is the main plasma regulator of the alternative pathway of complement. Genetic and acquired abnormalities in FH cause uncontrolled complement activation amplifying, with the consequent accumulation of complement components on the renal glomeruli. This leads to conditions suc...

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Detalles Bibliográficos
Autores principales: Casiraghi, Federica, Ordonez, Pamela Yossenaidy Rodriguez, Azzollini, Nadia, Todeschini, Marta, Rottoli, Daniela, Donadelli, Roberta, Gramignoli, Roberto, Benigni, Ariela, Noris, Marina, Remuzzi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194190/
https://www.ncbi.nlm.nih.gov/pubmed/34112227
http://dx.doi.org/10.1186/s13287-021-02386-7

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