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Hepatoma Cell-Derived Extracellular Vesicles Promote Liver Cancer Metastasis by Inducing the Differentiation of Bone Marrow Stem Cells Through microRNA-181d-5p and the FAK/Src Pathway

Bone marrow mesenchymal stem cells (BMSCs) are beneficial to repair the damaged liver. Tumor-derived extracellular vesicles (EV) are notorious in tumor metastasis. But the mechanism underlying hepatoma cell-derived EVs in BMSCs and liver cancer remains unclear. We hypothesize that hepatoma cell-deri...

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Detalles Bibliográficos
Autores principales: Wei, Huamei, Wang, Jianchu, Xu, Zuoming, Li, Wenchuan, Wu, Xianjian, Zhuo, Chenyi, Lu, Yuan, Long, Xidai, Tang, Qianli, Pu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194264/
https://www.ncbi.nlm.nih.gov/pubmed/34124029
http://dx.doi.org/10.3389/fcell.2021.607001