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Similar Genetic Architecture of Alzheimer’s Disease and Differential APOE Effect Between Sexes

Sex differences have been observed in the clinical manifestations of Alzheimer’s disease (AD) and elucidating their genetic basis is an active research topic. Based on autosomal genotype data of 7,216 men and 10,680 women, including 8,136 AD cases and 9,760 controls, we explored sex-related genetic...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Lo, Min-Tzu, Rosenthal, Sara Brin, Makowski, Carolina, Andreassen, Ole A., Salem, Rany M., McEvoy, Linda K., Fiecas, Mark, Chen, Chi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194397/
https://www.ncbi.nlm.nih.gov/pubmed/34122051
http://dx.doi.org/10.3389/fnagi.2021.674318