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Post-stroke Delivery of Valproic Acid Promotes Functional Recovery and Differentially Modifies Responses of Peri-Infarct Microglia

The specific role of peri-infarct microglia and the timing of its morphological changes following ischemic stroke are not well understood. Valproic acid (VPA) can protect against ischemic damage and promote recovery. In this study, we first determined whether a single dose of VPA after stroke could...

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Detalles Bibliográficos
Autores principales: Kuo, Tung-Tai, Wang, Vicki, Wu, Jui-Sheng, Chen, Yuan-Hao, Tseng, Kuan-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194695/
https://www.ncbi.nlm.nih.gov/pubmed/34122007
http://dx.doi.org/10.3389/fnmol.2021.639145