Answered and Unanswered Questions in Early-Stage Viral Vector Transduction Biology and Innate Primary Cell Toxicity for Ex-Vivo Gene Editing

Adeno-associated virus is a highly efficient DNA delivery vehicle for genome editing strategies that employ CRISPR/Cas9 and a DNA donor for homology-directed repair. Many groups have used this strategy in development of therapies for blood and immune disorders such as sickle-cell anemia and severe-c...

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Detalles Bibliográficos
Autores principales: Dudek, Amanda Mary, Porteus, Matthew Hebden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195279/
https://www.ncbi.nlm.nih.gov/pubmed/34122418
http://dx.doi.org/10.3389/fimmu.2021.660302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195279/
https://www.ncbi.nlm.nih.gov/pubmed/34122418
http://dx.doi.org/10.3389/fimmu.2021.660302

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