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Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca(2+)-binding photoprotein aequorin

The Ca(2+)-binding photoprotein aequorin is a complex of apoAequorin (apoprotein) and (S)-2-peroxycoelenterazine. Aequorin can be regenerated by the incubation of apoAequorin with coelenterazine and molecular oxygen (O(2)). In this study, to investigate the molecular recognition of apoAequorin for c...

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Detalles Bibliográficos
Autores principales: Inouye, Satoshi, Sumida, Yuto, Tomabechi, Yuri, Taguchi, Jumpei, Shirouzu, Mikako, Hosoya, Takamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195370/
https://www.ncbi.nlm.nih.gov/pubmed/34115795
http://dx.doi.org/10.1371/journal.pone.0251743