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Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca(2+)-binding photoprotein aequorin
The Ca(2+)-binding photoprotein aequorin is a complex of apoAequorin (apoprotein) and (S)-2-peroxycoelenterazine. Aequorin can be regenerated by the incubation of apoAequorin with coelenterazine and molecular oxygen (O(2)). In this study, to investigate the molecular recognition of apoAequorin for c...
Autores principales: | Inouye, Satoshi, Sumida, Yuto, Tomabechi, Yuri, Taguchi, Jumpei, Shirouzu, Mikako, Hosoya, Takamitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195370/ https://www.ncbi.nlm.nih.gov/pubmed/34115795 http://dx.doi.org/10.1371/journal.pone.0251743 |
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