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Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome

Adeno-associated virus (AAV) genome replication only occurs in the presence of a co-infecting helper virus such as adenovirus type 5 (AdV5) or herpes simplex virus type 1 (HSV-1). AdV5-supported replication of the AAV genome has been described to occur in a strand-displacement rolling hairpin replic...

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Detalles Bibliográficos
Autores principales: Meier, Anita Felicitas, Tobler, Kurt, Leisi, Remo, Lkharrazi, Anouk, Ros, Carlos, Fraefel, Cornel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195378/
https://www.ncbi.nlm.nih.gov/pubmed/34061891
http://dx.doi.org/10.1371/journal.ppat.1009638