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Biophysical analysis of drug efficacy on C. elegans models for neurodegenerative and neuromuscular diseases
Caenorhabditis elegans has emerged as a powerful model organism for drug screening due to its cellular simplicity, genetic amenability and homology to humans combined with its small size and low cost. Currently, high-throughput drug screening assays are mostly based on image-based phenotyping with t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195402/ https://www.ncbi.nlm.nih.gov/pubmed/34115761 http://dx.doi.org/10.1371/journal.pone.0246496 |