High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease

INTRODUCTION: Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection ar...

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Detalles Bibliográficos
Autores principales: Ketema, Ezra B., Gishen, Nigus Z., Hailu, Abraha, Leul, Abadi, Hadgu, Abera, Hagos, Kiflom, Berhane, Samual, Tsega, Temesgen, Page-Sharp, Madhu, Davis, Timothy ME, Moore, Brioni, Batty, Kevin T., Carapetis, Jonathan, Salman, Sam, Manning, Laurens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195421/
https://www.ncbi.nlm.nih.gov/pubmed/34115748
http://dx.doi.org/10.1371/journal.pntd.0009399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195421/
https://www.ncbi.nlm.nih.gov/pubmed/34115748
http://dx.doi.org/10.1371/journal.pntd.0009399

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