The ultrastructure of infectious L-type bovine spongiform encephalopathy prions constrains molecular models

Bovine spongiform encephalopathy (BSE) is a prion disease of cattle that is caused by the misfolding of the cellular prion protein (PrP(C)) into an infectious conformation (PrP(Sc)). PrP(C) is a predominantly α-helical membrane protein that misfolds into a β-sheet rich, infectious state, which has a...

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Detalles Bibliográficos
Autores principales: Kamali-Jamil, Razieh, Vázquez-Fernández, Ester, Tancowny, Brian, Rathod, Vineet, Amidian, Sara, Wang, Xiongyao, Tang, Xinli, Fang, Andrew, Senatore, Assunta, Hornemann, Simone, Dudas, Sandor, Aguzzi, Adriano, Young, Howard S., Wille, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195424/
https://www.ncbi.nlm.nih.gov/pubmed/34061899
http://dx.doi.org/10.1371/journal.ppat.1009628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195424/
https://www.ncbi.nlm.nih.gov/pubmed/34061899
http://dx.doi.org/10.1371/journal.ppat.1009628

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