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PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines. We coupled Positron Emission Tomography (PET) ima...

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Detalles Bibliográficos
Autores principales: Taylor, Roslyn A., Xiao, Sixia, Carias, Ann M., McRaven, Michael D., Thakkar, Divya N., Araínga, Mariluz, Allen, Edward J., Rogers, Kenneth A., Kumarapperuma, Sidath C., Gong, Siqi, Fought, Angela J., Anderson, Meegan R., Thomas, Yanique, Schneider, Jeffrey R., Goins, Beth, Fox, Peter, Villinger, Francois J., Ruprecht, Ruth M., Hope, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195437/
https://www.ncbi.nlm.nih.gov/pubmed/34061907
http://dx.doi.org/10.1371/journal.ppat.1009632