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PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure
Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines. We coupled Positron Emission Tomography (PET) ima...
Autores principales: | Taylor, Roslyn A., Xiao, Sixia, Carias, Ann M., McRaven, Michael D., Thakkar, Divya N., Araínga, Mariluz, Allen, Edward J., Rogers, Kenneth A., Kumarapperuma, Sidath C., Gong, Siqi, Fought, Angela J., Anderson, Meegan R., Thomas, Yanique, Schneider, Jeffrey R., Goins, Beth, Fox, Peter, Villinger, Francois J., Ruprecht, Ruth M., Hope, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195437/ https://www.ncbi.nlm.nih.gov/pubmed/34061907 http://dx.doi.org/10.1371/journal.ppat.1009632 |
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