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Molecular-scale spatio-chemical control of the activating-inhibitory signal integration in NK cells

The role of juxtaposition of activating and inhibitory receptors in signal inhibition of cytotoxic lymphocytes remains strongly debated. The challenge lies in the lack of tools that allow simultaneous spatial manipulation of signaling molecules. To circumvent this, we produced a nanoengineered multi...

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Detalles Bibliográficos
Autores principales: Toledo, Esti, Le Saux, Guillaume, Edri, Avishay, Li, Long, Rosenberg, Maor, Keidar, Yossi, Bhingardive, Viraj, Radinsky, Olga, Hadad, Uzi, Di Primo, Carmelo, Buffeteau, Thierry, Smith, Ana-Sunčana, Porgador, Angel, Schvartzman, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195486/
https://www.ncbi.nlm.nih.gov/pubmed/34117052
http://dx.doi.org/10.1126/sciadv.abc1640