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Molecular-scale spatio-chemical control of the activating-inhibitory signal integration in NK cells
The role of juxtaposition of activating and inhibitory receptors in signal inhibition of cytotoxic lymphocytes remains strongly debated. The challenge lies in the lack of tools that allow simultaneous spatial manipulation of signaling molecules. To circumvent this, we produced a nanoengineered multi...
Autores principales: | Toledo, Esti, Le Saux, Guillaume, Edri, Avishay, Li, Long, Rosenberg, Maor, Keidar, Yossi, Bhingardive, Viraj, Radinsky, Olga, Hadad, Uzi, Di Primo, Carmelo, Buffeteau, Thierry, Smith, Ana-Sunčana, Porgador, Angel, Schvartzman, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195486/ https://www.ncbi.nlm.nih.gov/pubmed/34117052 http://dx.doi.org/10.1126/sciadv.abc1640 |
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