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Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates inter-chromosomal movement

Hundreds of genes interact with the yeast nuclear pore complex (NPC), localizing at the nuclear periphery and clustering with co-regulated genes. Dynamic tracking of peripheral genes shows that they cycle on and off the NPC and that interaction with the NPC slows their sub-diffusive movement. Furthe...

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Detalles Bibliográficos
Autores principales: Sumner, Michael Chas, Torrisi, Steven B, Brickner, Donna G, Brickner, Jason H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195609/
https://www.ncbi.nlm.nih.gov/pubmed/34002694
http://dx.doi.org/10.7554/eLife.66238