Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer

The Aurora-A kinase regulates cell division, by controlling centrosome biology and spindle assembly. Cancer cells often display elevated levels of the kinase, due to amplification of the gene locus, increased transcription or post-translational modifications. Several inhibitors of Aurora-A activity...

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Detalles Bibliográficos
Autores principales: Naso, Francesco Davide, Boi, Dalila, Ascanelli, Camilla, Pamfil, Georgiana, Lindon, Catherine, Paiardini, Alessandro, Guarguaglini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195736/
https://www.ncbi.nlm.nih.gov/pubmed/33981003
http://dx.doi.org/10.1038/s41388-021-01766-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195736/
https://www.ncbi.nlm.nih.gov/pubmed/33981003
http://dx.doi.org/10.1038/s41388-021-01766-w

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