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Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer
The Aurora-A kinase regulates cell division, by controlling centrosome biology and spindle assembly. Cancer cells often display elevated levels of the kinase, due to amplification of the gene locus, increased transcription or post-translational modifications. Several inhibitors of Aurora-A activity...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195736/ https://www.ncbi.nlm.nih.gov/pubmed/33981003 http://dx.doi.org/10.1038/s41388-021-01766-w |