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A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment

BACKGROUND: In colon cancer, the location and density of tumor-infiltrating lymphocytes (TILs) can classify patients into low and high-risk groups for prognostication. While a commercially available ‘Immunoscore(®)’ exists, the incurred expenses and copyrights may prevent universal use. The aim of t...

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Detalles Bibliográficos
Autores principales: Lea, Dordi, Watson, Martin, Skaland, Ivar, Hagland, Hanne R., Lillesand, Melinda, Gudlaugsson, Einar, Søreide, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195795/
https://www.ncbi.nlm.nih.gov/pubmed/33439293
http://dx.doi.org/10.1007/s00262-020-02834-y