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Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primates

INTRODUCTION: The etiology of sporadic Alzheimer's disease (AD) requires non‐genetically modified animal models. METHODS: The relationship of tau phosphorylation to calcium‐cyclic adenosine monophosphate (cAMP)‐protein kinase A (PKA) dysregulation was analyzed in aging rhesus macaque dorsolater...

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Detalles Bibliográficos
Autores principales: Datta, Dibyadeep, Leslie, Shannon N., Wang, Min, Morozov, Yury M., Yang, Shengtao, Mentone, SueAnn, Zeiss, Caroline, Duque, Alvaro, Rakic, Pasko, Horvath, Tamas L., van Dyck, Christopher H., Nairn, Angus C., Arnsten, Amy F.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195842/
https://www.ncbi.nlm.nih.gov/pubmed/33829643
http://dx.doi.org/10.1002/alz.12325