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Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer’s disease (AD). Along AD progression, the accumulation of danger-associated molecular patterns (DAMPs) including beta-amyloid and hyperphosphorylated tau continuously stimulates microg...

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Detalles Bibliográficos
Autores principales: Lau, Shun-Fat, Fu, Amy K. Y., Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195901/
https://www.ncbi.nlm.nih.gov/pubmed/33847763
http://dx.doi.org/10.1007/s00018-021-03810-0