Evaluation of the Pharmacokinetic Interaction and Safety of Atogepant Co-Administered with Acetaminophen or Naproxen in Healthy Participants: A Randomized Trial

BACKGROUND: Atogepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist in development for preventive treatment of migraine. OBJECTIVE: To evaluate potential pharmacokinetic drug–drug interactions (DDIs), safety and tolerability of atogepant co-administered with acetaminophen or...

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Detalles Bibliográficos
Autores principales: Boinpally, Ramesh, Spaventa, John, Chen, Kayla, Butler, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195918/
https://www.ncbi.nlm.nih.gov/pubmed/33948911
http://dx.doi.org/10.1007/s40261-021-01034-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195918/
https://www.ncbi.nlm.nih.gov/pubmed/33948911
http://dx.doi.org/10.1007/s40261-021-01034-5

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