Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells

Bone marrow (BM) chimeric mice are a valuable tool in the field of immunology, with the genetic manipulation of donor cells widely used to study gene function under physiological and pathological settings. To date, however, BM chimera protocols require myeloablative conditioning of recipient mice, w...

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Detalles Bibliográficos
Autores principales: Ochi, Kiyosumi, Morita, Maiko, Wilkinson, Adam C., Iwama, Atsushi, Yamazaki, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195984/
https://www.ncbi.nlm.nih.gov/pubmed/34117255
http://dx.doi.org/10.1038/s41467-021-23763-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195984/
https://www.ncbi.nlm.nih.gov/pubmed/34117255
http://dx.doi.org/10.1038/s41467-021-23763-z

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