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Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9, CYP2C19, and CYP3A4 in a Thai population

Prior knowledge of allele frequencies of cytochrome P450 polymorphisms in a population is crucial for the revision and optimization of existing medication choices and doses. In the current study, the frequency of the CYP2C9*2, CYP2C9*3, CYP2C19*2, CYP2C19*3, CYP2C19*6, CYP2C19*17, and CYP3A4 (rs4646...

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Detalles Bibliográficos
Autores principales: Sukprasong, Rattanaporn, Chuwongwattana, Sumonrat, Koomdee, Napatrupron, Jantararoungtong, Thawinee, Prommas, Santirhat, Jinda, Pimonpan, Rachanakul, Jiratha, Nuntharadthanaphong, Nutthan, Jongjitsook, Nutcha, Puangpetch, Apichaya, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195986/
https://www.ncbi.nlm.nih.gov/pubmed/34117307
http://dx.doi.org/10.1038/s41598-021-90969-y