Comparison of the fertility of tumor suppressor gene-deficient C57BL/6 mouse strains reveals stable reproductive aging and novel pleiotropic gene

Tumor suppressor genes are involved in maintaining genome integrity during reproduction (e.g., meiosis). Thus, deleterious alleles in tumor suppressor-deficient mice would exhibit higher mortality during the perinatal period. A recent aging model proposes that perinatal mortality and age-related del...

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Detalles Bibliográficos
Autores principales: Kohzaki, Masaoki, Ootsuyama, Akira, Umata, Toshiyuki, Okazaki, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195996/
https://www.ncbi.nlm.nih.gov/pubmed/34117297
http://dx.doi.org/10.1038/s41598-021-91342-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195996/
https://www.ncbi.nlm.nih.gov/pubmed/34117297
http://dx.doi.org/10.1038/s41598-021-91342-9

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