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Dendritic spines are lost in clusters in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the loss of dendritic spines of pyramidal cells, which are the major...

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Detalles Bibliográficos
Autores principales: Mijalkov, Mite, Volpe, Giovanni, Fernaud-Espinosa, Isabel, DeFelipe, Javier, Pereira, Joana B., Merino-Serrais, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196005/
https://www.ncbi.nlm.nih.gov/pubmed/34117272
http://dx.doi.org/10.1038/s41598-021-91726-x