HSP-90/kinase complexes are stabilized by the large PPIase FKB-6

Protein kinases are important regulators in cellular signal transduction. As one major type of Hsp90 client, protein kinases rely on the ATP-dependent molecular chaperone Hsp90, which maintains their structure and supports their activation. Depending on client type, Hsp90 interacts with different co...

Descripción completa

Detalles Bibliográficos
Autores principales: Sima, Siyuan, Barkovits, Katalin, Marcus, Katrin, Schmauder, Lukas, Hacker, Stephan M., Hellwig, Nils, Morgner, Nina, Richter, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196007/
https://www.ncbi.nlm.nih.gov/pubmed/34117308
http://dx.doi.org/10.1038/s41598-021-91667-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196007/
https://www.ncbi.nlm.nih.gov/pubmed/34117308
http://dx.doi.org/10.1038/s41598-021-91667-5

Ejemplares similares