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Benchmarking microbiome transformations favors experimental quantitative approaches to address compositionality and sampling depth biases

While metagenomic sequencing has become the tool of preference to study host-associated microbial communities, downstream analyses and clinical interpretation of microbiome data remains challenging due to the sparsity and compositionality of sequence matrices. Here, we evaluate both computational an...

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Detalles Bibliográficos
Autores principales: Lloréns-Rico, Verónica, Vieira-Silva, Sara, Gonçalves, Pedro J., Falony, Gwen, Raes, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196019/
https://www.ncbi.nlm.nih.gov/pubmed/34117246
http://dx.doi.org/10.1038/s41467-021-23821-6