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Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver

Parenteral nutrition-associated cholestasis (PNAC) significantly limits the safety of intravenous parenteral nutrition (PN). Critically ill infants are highly vulnerable to PNAC-related morbidity and mortality, however the impact of hepatic immaturity on PNAC is poorly understood. We examined develo...

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Detalles Bibliográficos
Autores principales: Nghiem-Rao, T. Hang, Pfeifer, Courtney, Asuncion, Michelle, Nord, Joshua, Schill, Daniel, Pulakanti, Kirthi, Patel, Shailendra B., Cirillo, Lisa A., Rao, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196029/
https://www.ncbi.nlm.nih.gov/pubmed/34117281
http://dx.doi.org/10.1038/s41598-021-90510-1