CD38-specific Chimeric Antigen Receptor Expressing Natural Killer KHYG-1 Cells: A Proof of Concept for an “Off the Shelf” Therapy for Multiple Myeloma

Chimeric antigen receptor (CAR) T cells are highly successful in the treatment of hematologic malignancies. We recently generated affinity-optimized CD38CAR T cells, which effectively eliminate multiple myeloma (MM) cells with little or no toxicities against nonmalignant hematopoietic cells. The lac...

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Detalles Bibliográficos
Autores principales: Stikvoort, Arwen, van der Schans, Jort, Sarkar, Subhashis, Poels, Renée, Ruiter, Ruud, Naik, Jyoti, Yuan, Huipin, de Bruijn, Joost D., van de Donk, Niels W. C. J., Zweegman, Sonja, Themeli, Maria, Groen, Richard, O’Dwyer, Michael, Mutis, Tuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196092/
https://www.ncbi.nlm.nih.gov/pubmed/34131635
http://dx.doi.org/10.1097/HS9.0000000000000596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196092/
https://www.ncbi.nlm.nih.gov/pubmed/34131635
http://dx.doi.org/10.1097/HS9.0000000000000596

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