Analysis of the genomic landscape of yolk sac tumors reveals mechanisms of evolution and chemoresistance

Yolk sac tumors (YSTs) are a major histological subtype of malignant ovarian germ cell tumors with a relatively poor prognosis. The molecular basis of this disease has not been thoroughly characterized at the genomic level. Here we perform whole-exome and RNA sequencing on 41 clinical tumor samples...

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Detalles Bibliográficos
Autores principales: Zong, Xuan, Zhang, Ying, Peng, Xinxin, Cao, Dongyan, Yu, Mei, Wang, Jinhui, Li, Hongyue, Guo, Xuejiao, Liang, Han, Yang, Jiaxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196104/
https://www.ncbi.nlm.nih.gov/pubmed/34117242
http://dx.doi.org/10.1038/s41467-021-23681-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196104/
https://www.ncbi.nlm.nih.gov/pubmed/34117242
http://dx.doi.org/10.1038/s41467-021-23681-0

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