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Cas9 targeted enrichment of mobile elements using nanopore sequencing

Mobile element insertions (MEIs) are repetitive genomic sequences that contribute to genetic variation and can lead to genetic disorders. Targeted and whole-genome approaches using short-read sequencing have been developed to identify reference and non-reference MEIs; however, the read length hamper...

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Detalles Bibliográficos
Autores principales: McDonald, Torrin L., Zhou, Weichen, Castro, Christopher P., Mumm, Camille, Switzenberg, Jessica A., Mills, Ryan E., Boyle, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196195/
https://www.ncbi.nlm.nih.gov/pubmed/34117247
http://dx.doi.org/10.1038/s41467-021-23918-y