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Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease

BACKGROUND: Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, neuroinflammation, and neurodegeneration. Thus, targeting of t...

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Detalles Bibliográficos
Autores principales: Sun, Xiao-ying, Li, Ling-jie, Dong, Quan-Xiu, Zhu, Jie, Huang, Ya-ru, Hou, Sheng-jie, Yu, Xiao-lin, Liu, Rui-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196535/
https://www.ncbi.nlm.nih.gov/pubmed/34116706
http://dx.doi.org/10.1186/s12974-021-02182-3