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Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease
BACKGROUND: Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, neuroinflammation, and neurodegeneration. Thus, targeting of t...
Autores principales: | Sun, Xiao-ying, Li, Ling-jie, Dong, Quan-Xiu, Zhu, Jie, Huang, Ya-ru, Hou, Sheng-jie, Yu, Xiao-lin, Liu, Rui-tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196535/ https://www.ncbi.nlm.nih.gov/pubmed/34116706 http://dx.doi.org/10.1186/s12974-021-02182-3 |
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