Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells

HIV monoclonal antibodies for viral reservoir eradication strategies will likely need to recognize reactivated infected cells and potently drive Fc-mediated innate effector cell activity. We systematically characterize a library of 185 HIV-envelope-specific antibodies derived from 15 spontaneous HIV...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossignol, Evan D., Dugast, Anne-Sophie, Compere, Hacheming, Cottrell, Christopher A., Copps, Jeffrey, Lin, Shu, Cizmeci, Deniz, Seaman, Michael S., Ackerman, Margaret E., Ward, Andrew B., Alter, Galit, Julg, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196545/
https://www.ncbi.nlm.nih.gov/pubmed/34038720
http://dx.doi.org/10.1016/j.celrep.2021.109167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196545/
https://www.ncbi.nlm.nih.gov/pubmed/34038720
http://dx.doi.org/10.1016/j.celrep.2021.109167

Ejemplares similares