Cargando…
Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells
HIV monoclonal antibodies for viral reservoir eradication strategies will likely need to recognize reactivated infected cells and potently drive Fc-mediated innate effector cell activity. We systematically characterize a library of 185 HIV-envelope-specific antibodies derived from 15 spontaneous HIV...
Autores principales: | Rossignol, Evan D., Dugast, Anne-Sophie, Compere, Hacheming, Cottrell, Christopher A., Copps, Jeffrey, Lin, Shu, Cizmeci, Deniz, Seaman, Michael S., Ackerman, Margaret E., Ward, Andrew B., Alter, Galit, Julg, Boris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196545/ https://www.ncbi.nlm.nih.gov/pubmed/34038720 http://dx.doi.org/10.1016/j.celrep.2021.109167 |
Ejemplares similares
-
Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth
por: Cizmeci, Deniz, et al.
Publicado: (2021) -
Mining for humoral correlates of HIV control and latent reservoir size
por: Das, Jishnu, et al.
Publicado: (2020) -
Functional Compartmentalization of Antibodies in the Central Nervous System During Chronic HIV Infection
por: Spatola, Marianna, et al.
Publicado: (2022) -
Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
por: Bartsch, Yannic C., et al.
Publicado: (2021) -
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
por: Schoofs, Till, et al.
Publicado: (2019)