Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice

Soluble epoxide hydrolase (sEH) is abundant in the brain, is upregulated in type 2 diabetes mellitus (DM2), and is possible mediator of ischemic injury via the breakdown of neuroprotective epoxyeicosatrienoic acids (EETs). Prophylactic, pre-ischemic sEH blockade with 4-[[trans-4-[[(tricyclo[3.3.1.13...

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Detalles Bibliográficos
Autores principales: Davis, Catherine M., Zhang, Wenri H., Allen, Elyse M., Bah, Thierno M., Shangraw, Robert E., Alkayed, Nabil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196561/
https://www.ncbi.nlm.nih.gov/pubmed/34063817
http://dx.doi.org/10.3390/ijms22115419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196561/
https://www.ncbi.nlm.nih.gov/pubmed/34063817
http://dx.doi.org/10.3390/ijms22115419

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