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Multiscale Modeling of Wobble to Watson–Crick-Like Guanine–Uracil Tautomerization Pathways in RNA

Energetically unfavorable Watson–Crick (WC)-like tautomeric forms of nucleobases are known to introduce spontaneous mutations, and contribute to replication, transcription, and translation errors. Recent NMR relaxation dispersion techniques were able to show that wobble (w) G•U mispair exists in equ...

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Detalles Bibliográficos
Autores principales: Chandorkar, Shreya, Raghunathan, Shampa, Jaganade, Tanashree, Priyakumar, U. Deva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196565/
https://www.ncbi.nlm.nih.gov/pubmed/34063755
http://dx.doi.org/10.3390/ijms22115411