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Identification of Kaurane-Type Diterpenes as Inhibitors of Leishmania Pteridine Reductase I

The current treatments against Leishmania parasites present high toxicity and multiple side effects, which makes the control and elimination of leishmaniasis challenging. Natural products constitute an interesting and diverse chemical space for the identification of new antileishmanial drugs. To ide...

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Detalles Bibliográficos
Autores principales: Herrera-Acevedo, Chonny, Flores-Gaspar, Areli, Scotti, Luciana, Mendonça-Junior, Francisco Jaime Bezerra, Scotti, Marcus Tullius, Coy-Barrera, Ericsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196580/
https://www.ncbi.nlm.nih.gov/pubmed/34063939
http://dx.doi.org/10.3390/molecules26113076