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A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial of Oral Brincidofovir for Cytomegalovirus Prophylaxis in Allogeneic Hematopoietic Cell Transplantation

Cytomegalovirus (CMV) infection is a common complication of allogeneic hematopoietic cell transplantation (HCT). In this trial, we randomized adult CMV-seropositive HCT recipients without CMV viremia at screening 2:1 to receive brincidofovir or placebo until week 14 post-HCT. Randomization was strat...

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Detalles Bibliográficos
Autores principales: Marty, Francisco M., Winston, Drew J., Chemaly, Roy F., Mullane, Kathleen M., Shore, Tsiporah B., Papanicolaou, Genovefa A., Chittick, Greg, Brundage, Thomas M., Wilson, Chad, Morrison, Marion E., Foster, Scott A., Nichols, W. Garrett, Boeckh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196624/
https://www.ncbi.nlm.nih.gov/pubmed/30292744
http://dx.doi.org/10.1016/j.bbmt.2018.09.038