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Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant (18)F-Labelled σ(2) Receptor Ligand
The σ(2) receptor (transmembrane protein 97), which is involved in cholesterol homeostasis, is of high relevance for neoplastic processes. The upregulated expression of σ(2) receptors in cancer cells and tissue in combination with the antiproliferative potency of σ(2) receptor ligands motivates the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196714/ https://www.ncbi.nlm.nih.gov/pubmed/34064122 http://dx.doi.org/10.3390/ijms22115447 |