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Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States

INTRODUCTION: Vaginal rings are a promising approach to provide a woman‐centred, long‐acting HIV prevention strategy. Prior trials of a 25 mg dapivirine (DPV) ring have shown a favourable safety profile and approximately 30% risk reduction of HIV‐1 infection. Extended duration rings replaced every t...

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Detalles Bibliográficos
Autores principales: Liu, Albert Y, Dominguez Islas, Clara, Gundacker, Holly, Neradilek, Blazej, Hoesley, Craig, van der Straten, Ariane, Hendrix, Craig W, Beamer, May, Jacobson, Cindy E, McClure, Tara, Harrell, Tanya, Bunge, Katherine, Devlin, Brid, Nuttall, Jeremy, Spence, Patrick, Steytler, John, Piper, Jeanna M, Marzinke, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196716/
https://www.ncbi.nlm.nih.gov/pubmed/34118115
http://dx.doi.org/10.1002/jia2.25747