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Evaluation of Calyculin A Effect on γH2AX/53BP1 Focus Formation and Apoptosis in Human Umbilical Cord Blood Lymphocytes

Dephosphorylation inhibitor calyculin A (cal A) has been reported to inhibit the disappearance of radiation-induced γH2AX DNA repair foci in human lymphocytes. However, other studies reported no change in the kinetics of γH2AX focus induction and loss in irradiated cells. While apoptosis might inter...

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Detalles Bibliográficos
Autores principales: Zastko, Lucián, Račková, Anna, Petrovičová, Petra, Durdík, Matúš, Míšek, Jakub, Marková, Eva, Belyaev, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196852/
https://www.ncbi.nlm.nih.gov/pubmed/34067339
http://dx.doi.org/10.3390/ijms22115470