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Synthesis and Guest-Binding Properties of pH/Reduction Dual-Responsive Cyclophane Dimer

A water-soluble cyclophane dimer having two disulfide groups as a reduction-responsive cleavable bond as well as several acidic and basic functional groups as a pH-responsive ionizable group 1 was successfully synthesized. It was found that 1 showed pH-dependent guest-binding behavior. That is, 1 st...

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Detalles Bibliográficos
Autores principales: Hayashida, Osamu, Tanaka, Yudai, Miyazaki, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196905/
https://www.ncbi.nlm.nih.gov/pubmed/34067275
http://dx.doi.org/10.3390/molecules26113097