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Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly

Inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate 1 (IRAG1) is a substrate protein of the NO/cGMP-signaling pathway and forms a ternary complex with the cGMP-dependent protein kinase Iβ (PKGIβ) and the inositol triphosphate receptor I (IP(3)R-I). Functional studies about IRAG1 ex...

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Detalles Bibliográficos
Autores principales: Majer, Michael, Prueschenk, Sally, Schlossmann, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196906/
https://www.ncbi.nlm.nih.gov/pubmed/34064290
http://dx.doi.org/10.3390/ijms22115458