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Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations

Immunoglobulin (IG) loci harbor inter-individual allelic variants in many different germline IG variable, diversity and joining genes of the IG heavy (IGH), kappa (IGK) and lambda (IGL) loci, which together form the genetic basis of the highly diverse antigen-specific B-cell receptors. These allelic...

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Detalles Bibliográficos
Autores principales: Khatri, Indu, Berkowska, Magdalena A., van den Akker, Erik B., Teodosio, Cristina, Reinders, Marcel J. T., van Dongen, Jacques J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196923/
https://www.ncbi.nlm.nih.gov/pubmed/34120151
http://dx.doi.org/10.1038/s41435-021-00143-7